Authors: Timothy W. Russell, Nick Golding, Joel Hellewell, Sam Abbott, Carl A. B. Pearson, Kevin van Zandvoort, Christopher I. Jarvis, Hamish Gibbs, Yang Liu, Rosalind M. Eggo, W. John Edmunds, Adam J. Kucharski, CMMID COVID-19 working group

Published: July, 2020 in BMC Medicine

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Abstract

Asymptomatic or subclinical SARS-CoV-2 infections are often unreported, which means that confirmed case counts may not accurately reflect underlying epidemic dynamics. Understanding the level of ascertainment (the ratio of confirmed symptomatic cases to the true number of symptomatic individuals) and undetected epidemic progression is crucial to informing COVID-19 response planning, including the introduction and relaxation of control measures. Estimating case ascertainment over time allows for accurate estimates of specific outcomes such as seroprevalence, which is essential for planning control measures.

Cite

@article{russell_reconstructing_2020,
	title = {Reconstructing the early global dynamics of under-ascertained {COVID}-19 cases and infections},
	volume = {18},
	issn = {1741-7015},
	url = {https://doi.org/10.1186/s12916-020-01790-9},
	doi = {10.1186/s12916-020-01790-9},
	abstract = {Asymptomatic or subclinical {SARS}-{CoV}-2 infections are often unreported, which means that confirmed case counts may not accurately reflect underlying epidemic dynamics. Understanding the level of ascertainment (the ratio of confirmed symptomatic cases to the true number of symptomatic individuals) and undetected epidemic progression is crucial to informing {COVID}-19 response planning, including the introduction and relaxation of control measures. Estimating case ascertainment over time allows for accurate estimates of specific outcomes such as seroprevalence, which is essential for planning control measures.},
	pages = {332},
	number = {1},
	journaltitle = {{BMC} Medicine},
	shortjournal = {{BMC} Medicine},
	author = {Russell, Timothy W. and Golding, Nick and Hellewell, Joel and Abbott, Sam and Wright, Lawrence and Pearson, Carl A. B. and van Zandvoort, Kevin and Jarvis, Christopher I. and Gibbs, Hamish and Liu, Yang and Eggo, Rosalind M. and Edmunds, W. John and Kucharski, Adam J. and Deol, Arminder K. and Villabona-Arenas, C. Julian and Jombart, Thibaut and O’Reilly, Kathleen and Munday, James D. and Meakin, Sophie R. and Lowe, Rachel and Gimma, Amy and Endo, Akira and Nightingale, Emily S. and Medley, Graham and Foss, Anna M. and Knight, Gwenan M. and Prem, Kiesha and Hué, Stéphane and Diamond, Charlie and Rudge, James W. and Atkins, Katherine E. and Auzenbergs, Megan and Flasche, Stefan and Houben, Rein M. G. J. and Quilty, Billy J. and Klepac, Petra and Quaife, Matthew and Funk, Sebastian and Leclerc, Quentin J. and Emery, Jon C. and Jit, Mark and Simons, David and Bosse, Nikos I. and Procter, Simon R. and Sun, Fiona Yueqian and Clifford, Samuel and Sherratt, Katharine and Rosello, Alicia and Davies, Nicholas G. and Brady, Oliver and Tully, Damien C. and Gore-Langton, Georgia R. and {CMMID COVID-19 working group}},
	urldate = {2023-09-18},
	date = {2020-10-22},
	keywords = {Case ascertainment, {COVID}-19, Outbreak analysis, {SARS}-{CoV}-2, Situational awareness, Surveillance, Under-reporting},
	file = {Full Text PDF:/Users/hamishgibbs/Zotero/storage/P8YRJYXP/Russell et al. - 2020 - Reconstructing the early global dynamics of under-.pdf:application/pdf;Snapshot:/Users/hamishgibbs/Zotero/storage/WTW4AFYV/s12916-020-01790-9.html:text/html},
}